Good Laboratory Practice (GLP)

Good Laboratory Practice (GLP)


Good Laboratory Practice: Ensuring Integrity in Safety Research Integrity

Good Laboratory Practice (GLP) is a globally recognized quality system that ensures the consistency, reliability, and integrity of non-clinical laboratory studies supporting product safety assessments. It plays a critical role in safeguarding public health and environmental safety by establishing a foundation of trust for data used in risk evaluations.

GLP in an Evolving World

The ongoing creation of new chemicals, devices, and substances highlights the increasing demand for rigorous safety testing. To balance potential benefits with potential risks – and crucially, to maintain public support – the data derived from this testing must be of the utmost quality. GLP is the cornerstone of this process, promoting data integrity, reproducibility, and transparency in research.

The Rise of Global GLP

Early variations in national Good Laboratory Practice (GLP) requirements highlighted the need for international harmonization. The Organisation for Economic Co-operation and Development (OECD) took the lead, establishing a common framework for GLP principles. This promotes efficient collaboration, mutual data acceptance, and ensures GLP standards remain adaptable to evolving technologies and testing requirements.

The Role of the OECD in Harmonizing GLP Standards

While individual countries maintain national GLP guidelines, the Organisation for Economic Co-operation and Development (OECD) sets the internationally accepted standard with its Principles of GLP. Developed through international consensus, the OECD's Principles promote:
Mutual Acceptance of Data (MAD): Streamlines chemical safety assessments and reduces trade barriers.
Global Collaboration: Creates a foundation for international collaboration on safety research.

The Importance of Data Integrity and the Economic Impact of GLP

The central pillar of GLP is data integrity. Reliable data enables sound safety assessments and is essential for international cooperation. As the OECD emphasizes, "If individual countries can confidently rely on test data developed in other countries, duplicative testing can be avoided, thereby saving time and resources… [GLP] further improve[s] the protection of human health and the environment." Thus, GLP plays a vital role not only in safeguarding public well-being but also in fostering economic growth among OECD member states.

Scope of OECD GLP Principles

The OECD Principles on GLP apply broadly to the following areas:

Regulatory Studies: All non-clinical health and environmental safety studies required for product registration fall under GLP's scope.
Test Items: GLP principles pertain to the safety assessment of pharmaceuticals, pesticides, food additives, cosmetic products, veterinary drugs, industrial chemicals and medical devices.
Test Environments: Studies may be performed in a variety of settings, including laboratories, greenhouses, and field environments.

Nanolab: Your Partner in Global Compliance
GLP, MAD, and TURKAK Accreditation

Our commitment to GLP principles is your key to global markets. Our GLP facilities are accredited by TÜRKAK, the only accreditation institution operating in accordance with OECD principles in Turkey. This ensures the comprehensive test data generated in our facilities gains international recognition. Through the OECD's Mutual Acceptance of Data (MAD) system, you can be confident that our results will pave the way for smooth product approvals worldwide, eliminating redundant testing and saving you time and resources.

Nanolab Facilities: Your Gateway to Global GLP Compliance

In Istanbul, physical, chemical, and in vitro laboratory, providing a wide range of testing capabilities. For advanced research needs, our Edirne branch houses a dedicated in vivo animal experiments center, ensuring the highest standards in ethical and GLP-compliant animal studies.