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EN 14476: Chemical disinfectants and antiseptics - Virus killing quantitative suspension test for chemical disinfectants and antiseptics used in medicine
The aim of the standard is to evaluate whether a chemical disinfectant formulation is capable of a reduction in the number of viral particles infecting on suitable human-derived host cells.
Application Area
- It can be applied for products with claimed disinfectant efficacy against viruses.
- It can be applied to products to be used for surface, skin or industrial disinfection.
- It can be applied for chemical disinfectants and antiseptics to be used in areas and situations where disinfection or antiseptic care is available: Hospitals, schools, kindergartens and nursing homes and workplaces, laundries and kitchens that provide products to patients in public areas and homes ...
A test based on 5 steps is performed to verify virucidal activity:
- Calculation of virus titer (virus check)
- Measurement of the cytotoxicity of the disinfectant tested
- Detection of cellular susceptibility to the virus
- Neutralization control of the tested disinfectant
- Virus inactivation in 30 minutes and 60 minutes contact time with formaldehyde
When the above-mentioned test procedures meet the method criteria and the tested disinfectant meets the 4 log reduction compared to the initial virus titer at the end of the contact time with the virus, it can be said "Disinfectant is Effective Against Virus .
